Mouse survival data. All mice (6/6) that did not receive C. difficile survived for the duration of the study. As shown, 100% of mice treated with BC30 survived on study day 13, while 2 mice treated with vehicle did not survive on that day (92.3% survival). By day 14, 21/23 mice survived in the BC30/C. difficile treatment group, while 23/26 mice survived in the vehicle/C. difficile treatment group. Therefore, the cumulative survival rates in the study were: 100% (Vehicle/no C. difficile), 88.5% (Vehicle/C. difficile) and 91.3% (BC30/C. difficile). However, there was not a statistically significant difference in the survival rate between any of the treatment groups.
Fitzpatrick et al. Gut Pathogens 2011 3:16 doi:10.1186/1757-4749-3-16