Figure 7.

Estimated odds ratio, with 95% CI, in subjects without clinically-definite parkinsonism, for presence of a given sign, if serum immunoglobulin concentration doubled. Concentrations adjusted to age 60 years and as if all subjects male. Statistical significance of associations with bradykinesia and postural abnormality are, for IgM p = 0.001 & 0.8; for IgG 0.02 & 0.003; for IgA 0.001 & 0.001; for IgA1 0.004 & 0.001; for IgA2 0.2 & 0.07, respectively. Regarding rigidity, presence of activation phenomenon associated with IgA (OR = 1.7 (1.1, 2.6), p = 0.01) and IgA1 (1.6 (1.1, 2.3), p = 0.02).